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Choosing Medication Alternatives During Breastfeeding, Avoiding Alternative Facts : LactMed ® Update / Philip O. Anderson in Breastfeeding Medicine, Vol. 12, n°6 (Juillet - Août 2017)
Titre : Choosing Medication Alternatives During Breastfeeding, Avoiding Alternative Facts : LactMed ® Update Type de document : texte imprimé Auteurs : Philip O. Anderson, Auteur Année de publication : 2017 Article en page(s) : pp. 328-330 Langues : Anglais (eng) Catégories : Anti inflammatoire
Note de contenu : "Most drugs studied in nursing mothers present a low risk for the breastfed infant. But some drugs have more suitable alternatives available, often because of more extensive published safety data. In these cases, similar medications are listed in the “Alternate Drugs to Consider” section at the end of the LactMed record, just before the references. These records are easily accessed by clicking on the drug names, which are linked directly to the corresponding LactMed record. Some of the more common therapeutic dilemmas that might have better alternatives are addressed in this column. Additional information and documentation can be found in the corresponding LactMed records." [Présentation de l'auteur] Permalink :
in Breastfeeding Medicine > Vol. 12, n°6 (Juillet - Août 2017) . - pp. 328-330[article]Coagulase-Negative Staphylococci in Human Milk From Mothers of Preterm Compared With Term Neonates / Hiie Soeorg in Journal of Human Lactation, Vol. 33, n°2 (Mai 2017)
Titre : Coagulase-Negative Staphylococci in Human Milk From Mothers of Preterm Compared With Term Neonates Type de document : texte imprimé Auteurs : Hiie Soeorg, Auteur ; Tuuli Metsvaht, Auteur ; Imbi Eelmae, Auteur Année de publication : 2017 Article en page(s) : pp. 329-340 Langues : Anglais (eng) Catégories : Composition du lait
Nourrisson et enfant de 0 à 2 ans
Nouveau-né à terme
Prématuré (avant 37 semaines)
Résumé : "Background:
Human milk is the preferred nutrition for neonates and a source of bacteria.
The authors aimed to characterize the molecular epidemiology and genetic content of staphylococci in the human milk of mothers of preterm and term neonates.
Staphylococci were isolated once per week in the 1st month postpartum from the human milk of mothers of 20 healthy term and 49 preterm neonates hospitalized in the neonatal intensive care unit. Multilocus variable-number tandem-repeats analysis and multilocus sequence typing were used. The presence of the mecA gene, icaA gene of the ica-operon, IS256, and ACME genetic elements was determined by PCR.
The human milk of mothers of preterm compared with term neonates had higher counts of staphylococci but lower species diversity. The human milk of mothers of preterm compared with term neonates more often contained Staphylococcus epidermidis mecA (32.7% vs. 2.6%), icaA (18.8% vs. 6%), IS256 (7.9% vs. 0.9%), and ACME (15.4% vs. 5.1%), as well as Staphylococcus haemolyticus mecA (90.5% vs. 10%) and IS256 (61.9% vs. 10%). The overall distribution of multilocus variable-number tandem-repeats analysis (MLVA) types and sequence types was similar between the human milk of mothers of preterm and term neonates, but a few mecA-IS256-positive MLVA types colonized only mothers of preterm neonates. Maternal hospitalization within 1 month postpartum and the use of an arterial catheter or antibacterial treatment in the neonate increased the odds of harboring mecA-positive staphylococci in human milk.
Limiting exposure of mothers of preterm neonates to the hospital could prevent human milk colonization with more pathogenic staphylococci." [Résumé de l'auteur]
in Journal of Human Lactation > Vol. 33, n°2 (Mai 2017) . - pp. 329-340[article]Microbial Diversity in Milk of Women With Mastitis: Potential Role of Coagulase-Negative Staphylococci, Viridans Group Streptococci, and Corynebacteria / Pilar Mediano in Journal of Human Lactation, Vol. 33, n°2 (Mai 2017)
Titre : Microbial Diversity in Milk of Women With Mastitis: Potential Role of Coagulase-Negative Staphylococci, Viridans Group Streptococci, and Corynebacteria Type de document : texte imprimé Auteurs : Pilar Mediano, Auteur ; Leonides Fernandez, Auteur ; Esther Jimenez, Auteur Année de publication : 2017 Article en page(s) : pp. 309-318 Langues : Anglais (eng) Catégories : Bactérie
Composition du lait
Résumé : "Background:
Lactational mastitis constitutes a significant cause of premature weaning. However, its etiology, linked to the presence of pathogenic microorganisms, has been scarcely reported.
The aim of this study was to describe the microbial diversity in milk samples from women suffering from lactational mastitis and to identify more accurately a collection of isolates belonging to coagulase-negative staphylococci, streptococci, and coryneform bacteria.
This is a cross-sectional descriptive one-group study. A total of 5,009 isolates from 1,849 mastitis milk samples was identified by culture, biochemical, and/or molecular methods at the species or genus level. A more precise identification of a collection of 211 isolates was carried out by 16S rRNA gene sequencing.
Mean total bacterial count in milk samples was 4.11 log10 colony-forming units/ml, 95% confidence interval [4.08, 4.15]. Staphylococcus epidermidis was the most common species being isolated from 91.56% of the samples, whereas Staphylococcus aureus was detected in 29.74%. Streptococci and corynebacteria constituted the second (70.20%) and third (16.60%) most prevalent bacterial groups, respectively, found in this study. In contrast, Candida spp. was present in only 0.54% of the samples. Sequencing of the 16S rRNA gene revealed a high diversity of bacterial species among identified isolates.
Many coagulase-negative staphylococci, viridans group streptococci, and corynebacteria, usually dismissed as contaminant bacteria, may play an important role as etiologic agents of mastitis. Proper diagnosis of mastitis should be established after performing microbiological testing of milk based on standardized procedures. A reliable analysis must identify the mastitis-causing pathogen(s) at the species level and its(their) concentration(s)." [Résumé de l'auteur]
in Journal of Human Lactation > Vol. 33, n°2 (Mai 2017) . - pp. 309-318[article]Pharmacokinetics of Teicoplanin in a Breastfeeding Mother / François Fraissinet in Breastfeeding Medicine, Vol. 12, n°4 (Mai 2017)
Titre : Pharmacokinetics of Teicoplanin in a Breastfeeding Mother Type de document : texte imprimé Auteurs : François Fraissinet, Auteur ; Marine Lesourd, Auteur ; David Metsu, Auteur ; Peggy Gandia, Auteur Année de publication : 2017 Article en page(s) : pp. 244-246 Langues : Anglais (eng) Catégories : Antibiotique
Composition du lait
Mots-clés : téicoplanine Note de contenu : "To the Editor:
In their article entitled “Teicoplanin Use During Breastfeeding,” Kaplan et al.1 describe the outcome of an infant who was breastfed during his mother's short-term intravenous teicoplanin treatment. The authors mention that the main limitation of their case was the lack of information on teicoplanin concentrations in the mother's milk and serum." [extrait de l'article]
in Breastfeeding Medicine > Vol. 12, n°4 (Mai 2017) . - pp. 244-246[article]