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n°135 - Juin 2018 (Bulletin de Les Dossiers de l'Allaitement)
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaireOral Administration to Nursing Women of Lactobacillus fermentum CECT5716 Prevents Lactational Mastitis Development: A Randomized Controlled Trial / José A. Hurtado in Breastfeeding Medicine, Vol. 12, n°4 (Mai 2017)
Titre : Oral Administration to Nursing Women of Lactobacillus fermentum CECT5716 Prevents Lactational Mastitis Development: A Randomized Controlled Trial Type de document : texte imprimé Auteurs : José A. Hurtado, Auteur ; José A. Maldonado-Lobon, Auteur ; M. Paz Diaz-Ropero, Auteur ; PROLAC Group, Auteur Année de publication : 2017 Article en page(s) : pp. 202-209 Langues : Anglais (eng) Catégories : Essai contrôlé randomisé Etude
Lactation (thérapeutique médicameneuse)
Trouble de la lactation
Résumé : "Objective: The objective of this study is to evaluate the preventive effect of oral administration of Lactobacillus fermentum CECT5716 on mastitis incidence in lactating women.
Methods: A randomized double-blinded controlled trial that included 625 women was conducted. Women who received preventive dose of antibiotic in the context of delivery were recruited 1–6 days after childbirth and randomly assigned to a group. Probiotic group received 1 capsule/day containing L. fermentum 3 × 109 CFU, control group received 1 placebo capsule/day containing maltodextrin. The intervention period was 16 weeks. The primary outcome of the study was the incidence of clinical mastitis defined as at least two out of the three breast symptoms (pain, redness, and lump) and at least one of fever or flu-like symptoms (shivering, hot sweats, or aches).
Results: Two hundred ninety-one women completed 16 weeks of treatment. Sixteen women in the probiotic group developed mastitis versus 30 women in the control group (odds ratio = 0.531; p = 0.058). Incidence rate of mastitis in the probiotic group was significantly lower than that in the control group (IR = 0.130 in the probiotic group versus IR = 0.263 in the control group; p = 0.021). Therefore, the oral administration of L. fermentum CECT5716 during lactation decreased by 51% the incidence rate of clinical mastitis. Staphylococcus spp. load at the end of intervention was significantly lower in breast milk of women in the probiotic group than in breast milk of women in the control group (p = 0.025).
Conclusion: Consumption of the probiotic strain L. fermentum CECT5716 might be used during breastfeeding as an efficient strategy to prevent development of lactational mastitis in women." [Résumé de l'auteur]
in Breastfeeding Medicine > Vol. 12, n°4 (Mai 2017) . - pp. 202-209[article]Relationships Among Microbial Communities, Maternal Cells, Oligosaccharides, and Macronutrients in Human Milk / Janet E. Williams in Journal of Human Lactation, Vol. 33, n°3 (Août 2017)
Titre : Relationships Among Microbial Communities, Maternal Cells, Oligosaccharides, and Macronutrients in Human Milk Type de document : texte imprimé Auteurs : Janet E. Williams, Auteur ; J. Price Williams, Auteur Année de publication : 2017 Langues : Anglais (eng) Catégories : Cellule
Composition du lait
Résumé : "Background:
Human milk provides all essential nutrients necessary for early life and is rich in nonnutrients, maternally derived (host) cells, and bacteria, but almost nothing is known about the interplay among these components.
The primary objective of this research was to characterize relationships among macronutrients, maternal cells, and bacteria in milk.
Milk samples were collected from 16 women and analyzed for protein, lipid, fatty acid, lactose, and human milk oligosaccharide concentrations. Concentrations of maternal cells were determined using microscopy, and somatic cell counts were enumerated. Microbial ecologies were characterized using culture-independent methods.
Absolute and relative concentrations of maternal cells were mostly consistent within each woman as were relative abundances of bacterial genera, and there were many apparent relationships between these factors. For instance, relative abundance of Serratia was negatively associated with somatic cell counts (r = –.47, p < .0001) and neutrophil concentration (r = –.38, p < .0006). Concentrations of several oligosaccharides were correlated with maternally derived cell types as well as somatic cell counts; for example, lacto-N-tetraose and lacto-N-neotetraose were inversely correlated with somatic cell counts (r = –.64, p = .0082; r = –.52, p = .0387, respectively), and relative abundance of Staphylococcus was positively associated with total oligosaccharide concentration (r = .69, p = .0034). Complex relationships between milk nutrients and bacterial community profile, maternal cells, and milk oligosaccharides were also apparent.
These data support the possibility that profiles of maternally derived cells, nutrient concentrations, and the microbiome of human milk might be interrelated." [Résumé de l'auteur]
in Journal of Human Lactation > Vol. 33, n°3 (Août 2017)[article]The Impact of Storage Conditions on the Stability of Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis Bb12 in Human Milk / Anastasia Mantziari in Breastfeeding Medicine, Vol 12, n°9 (Novembre 2017)
Titre : The Impact of Storage Conditions on the Stability of Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis Bb12 in Human Milk Type de document : texte imprimé Auteurs : Anastasia Mantziari, Auteur ; Juhani Aakko, Auteur ; Himanshu Kumar, Auteur ; Satu Tölkkö, Auteur ; Elloise Du Toit, Auteur ; Seppo Salminen, Auteur ; Erika Isolauri, Auteur ; Samuli Rautava, Auteur Année de publication : 2017 Article en page(s) : pp. 566-569 Langues : Anglais (eng) Catégories : Composition du lait
Conservation du lait
Résumé : "Human milk is the optimal source of complete nutrition for neonates and it also guides the development of infant gut microbiota. Importantly, human milk can be supplemented with probiotics to complement the health benefits of breastfeeding. Storage of human milk for limited periods of time is often unavoidable, but little is known about the effect of different storage conditions (temperature) on the viability of the added probiotics. Therefore, in this study, we evaluated how different storage conditions affect the viability of two specific widely used probiotics, Lactobacillus rhamnosus GG (LGG) and Bifidobacterium animalis subsp. lactis (Bb12), in human milk by culturing and quantitative polymerase chain reaction. Our results indicate that LGG and Bb12 remained stable throughout the storage period. Thus, we conclude that human milk offers an appropriate matrix for probiotic supplementation."[résumé de l'auteur] Permalink :
in Breastfeeding Medicine > Vol 12, n°9 (Novembre 2017) . - pp. 566-569[article]