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Cellular Components, Including Stem-Like Cells, of Preterm Mother's Mature Milk as Compared with Those in Her Colostrum: A Pilot Study / Pankaj Kaingade in Breastfeeding Medicine, Vol 12, n°7 (Septembre 2017)
Titre : Cellular Components, Including Stem-Like Cells, of Preterm Mother's Mature Milk as Compared with Those in Her Colostrum: A Pilot Study Type de document : texte imprimé Auteurs : Pankaj Kaingade, Auteur ; Indumathi Somasundaram, Auteur ; Akshita Sharma, Auteur Année de publication : 2017 Article en page(s) : pp. 446-449 Langues : Anglais (eng) Catégories : Anticorps
Composition du lait
Grand prématuré (avant 34 semaines)
Lait maternel mature
Résumé : "Purpose and Study Objective: Whether the preterm mothers' mature milk retains the same cellular components as those in colostrum including stem-like cell, cell adhesion molecules, and immune cells.
Participants: A total of five preterm mothers were recruited for the study having an average age of 30.2 years and gestational age of 29.8 weeks from the Pristine Women's Hospital, Kolhapur. Colostrum milk was collected within 2–5 days and matured milk was collected 20–30 days after delivery from the same mothers.
Methodology: Integral cellular components of 22 markers including stem cells, immune cells, and cell adhesion molecules were measured using flowcytometry.
Outcome: Preterm mature milk was found to possess higher expressions of hematopoietic stem cells, mesenchymal stem-like cells, immune cells, few cell adhesion molecules, and side population cells than colostrum.
Conclusion: The increased level of these different cell components in mature milk may be important in the long-term preterm baby's health growth. Further similar research in a larger population of various gestational ages and lactation stages of preterm mothers is warranted to support these pilot findings."[résumé de l'auteur]
in Breastfeeding Medicine > Vol 12, n°7 (Septembre 2017) . - pp. 446-449[article]Relationships Among Microbial Communities, Maternal Cells, Oligosaccharides, and Macronutrients in Human Milk / Janet E. Williams in Journal of Human Lactation, Vol. 33, n°3 (Août 2017)
Titre : Relationships Among Microbial Communities, Maternal Cells, Oligosaccharides, and Macronutrients in Human Milk Type de document : texte imprimé Auteurs : Janet E. Williams, Auteur ; J. Price Williams, Auteur Année de publication : 2017 Langues : Anglais (eng) Catégories : Cellule
Composition du lait
Résumé : "Background:
Human milk provides all essential nutrients necessary for early life and is rich in nonnutrients, maternally derived (host) cells, and bacteria, but almost nothing is known about the interplay among these components.
The primary objective of this research was to characterize relationships among macronutrients, maternal cells, and bacteria in milk.
Milk samples were collected from 16 women and analyzed for protein, lipid, fatty acid, lactose, and human milk oligosaccharide concentrations. Concentrations of maternal cells were determined using microscopy, and somatic cell counts were enumerated. Microbial ecologies were characterized using culture-independent methods.
Absolute and relative concentrations of maternal cells were mostly consistent within each woman as were relative abundances of bacterial genera, and there were many apparent relationships between these factors. For instance, relative abundance of Serratia was negatively associated with somatic cell counts (r = –.47, p < .0001) and neutrophil concentration (r = –.38, p < .0006). Concentrations of several oligosaccharides were correlated with maternally derived cell types as well as somatic cell counts; for example, lacto-N-tetraose and lacto-N-neotetraose were inversely correlated with somatic cell counts (r = –.64, p = .0082; r = –.52, p = .0387, respectively), and relative abundance of Staphylococcus was positively associated with total oligosaccharide concentration (r = .69, p = .0034). Complex relationships between milk nutrients and bacterial community profile, maternal cells, and milk oligosaccharides were also apparent.
These data support the possibility that profiles of maternally derived cells, nutrient concentrations, and the microbiome of human milk might be interrelated." [Résumé de l'auteur]
in Journal of Human Lactation > Vol. 33, n°3 (Août 2017)[article]Stem-Like Cell Characteristics from Breast Milk of Mothers with Preterm Infants as Compared to Mothers with Term Infants in Breastfeeding Medicine, Vol. 12, n°3 (Avril 2017)
Titre : Stem-Like Cell Characteristics from Breast Milk of Mothers with Preterm Infants as Compared to Mothers with Term Infants Type de document : texte imprimé Année de publication : 2017 Langues : Anglais (eng) Catégories : Cellule
Composition du lait
Croissance et développement
Nourrisson et enfant de 0 à 2 ans
Nouveau-né à terme
Prématuré (avant 37 semaines)
in Breastfeeding Medicine > Vol. 12, n°3 (Avril 2017)[article]