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Auteur Philip O. Anderson |
Documents disponibles écrits par cet auteur (55)
Article : texte imprimé
Several genetic diseases have had advances in treatment, including some new drugs. This column will focus on a few of these drug therapies and their implications for breastfeeding. More detailed information and references on specific drugs can b[...]Article : texte imprimé
Raynaud's phenomenon (RP) occurs in 35% of the population, with the rate of occurrence in women about four times that in men. It is caused by vasospasm of the blood vessels in the extremities, including the nipple. RP of the nipple can be extre[...]Article : texte imprimé
Drug treatment of RA need not be a barrier to breastfeeding; however, careful drug selection is important. Low-dose methotrexate is a mainstay of therapy, and limited data have found no indication of toxicity in breastfed infants, but more data [...]Article : texte imprimé
The plethora of new drugs to treat hepatitis presents a confusing array of options to treat the nursing mother. LactMed has recently undertaken an extensive review of these drugs to put them into a consistent context. [extrait de l'article]Article : texte imprimé
Discussion of medication use during breastfeeding usually centers around potential harm to the nursing infant. However, another important consideration is that of drugs that interfere with lactation. These can be divided into two subcategories: [...]Article : texte imprimé
This column discusses medications that affect lactation when given postpartum. The previous column discussed medications that affect the establishment of lactation when given before or during delivery. Additional details and literature reference[...]Article : texte imprimé
Information on general anesthesia and breastfeeding is incomplete, and often of poor quality, but some generalizations can be made. General anesthesia might delay lactation postoperatively somewhat, but nursing right before anesthesia might redu[...]Article : texte imprimé
Most drugs used to treat IBS are acceptable to use during breastfeeding. Although several medications used in IBS have no information on use in nursing mothers, they appear to pose low risk to the breastfed infant. Dicyclomine and eluxadoline sh[...]Article : texte imprimé
Herbal medication use during breastfeeding has not been well studied, but a few cases of adverse reactions in breastfed infants have been reported. Herbals can adversely affect the nursing mother in several ways, including direct adverse effects[...]Article : texte imprimé
The LactMed database contains information on drugs to which breastfeeding mothers may be exposed, and the possible adverse effects of those medications in the nursing infant. LactMed is written under contract with the Specialized Information Ser[...]Article : document cartographique imprimé
Clinicians involved with breastfeeding have probably heard the generalization that most drugs are compatible with breastfeeding except for cancer chemotherapy and radioactive agents. In fact, as with most broad generalizations, this statement is[...]Article : texte imprimé
Constipation is not uncommon in nursing mothers, especially in the immediate postpartum period wherein some constipation is the result of prescribed opioids. A wide variety of products are available to prevent and treat constipation, ranging fro[...]NouveautéArticle : texte imprimé
Lidocaine and bupivacaine have extensive documented use in nursing mothers and are the preferred injectable local anesthetics during breastfeeding. Topical anesthetics known to cause systemic toxicity after oral ingestion, such as benzocaine, co[...]Article : texte imprimé
No routine vaccines are contraindicated in nursing mothers. Yellow fever vaccine should not be given to mothers who are breastfeeding an infantArticle : texte imprimé
For information on the use and safety of drugs in nursing mothers, the answers you get also depend on where you look for the answers. Several studies have compared the information provided in different sources. A 2007 article found wide variatio[...]Article : texte imprimé
It is feasible for migraineurs to breastfeed. If nondrug alternatives are ineffective, several prophylactic drugs such as certain anticonvulsants, beta-blockers, and onabotulinumtoxinA are safe for the breastfed infant. Although the new injectab[...]Article : texte imprimé
The conventional model of drug passage into breastmilk states that large molecules such as maternal immunoglobulins can pass into colostrum because spaces between mammary epithelial cells are open. Then, these pores begin to close at the onset o[...]Article : texte imprimé
Overall, several generalizations can be made: (1) most mothers receiving mAbs have unmeasurable or extremely low levels of the mAb in their breast milk; (2) about half of the mAb will be digested in the infant's tract; (3) negligible amounts of [...]Article : texte imprimé
The passage of food-borne toxins into breast milk is poorly documented, but appears to be possible and quite dangerous with some maternal poisonings. It is safest to assume that all of the most deadly toxins can potentially be transmitted to the[...]Article : document cartographique imprimé
Most radiopharmaceuticals consist of two parts: the radioactive isotope and a pharmacologically inert carrier molecule to which it is attached. The carrier molecule is designed to take the radiopharmaceutical to its intended target in the body b[...]Article : texte imprimé
Of the wide range of drugs used to treat respiratory conditions, few have any serious concerns for use in nursing mothers. Inhaled drugs used for respiratory conditions, including nasal sprays, pose little or no risk to the breastfed infant. Ora[...]Article : texte imprimé
The use of personal care products poses some potential risks to the breastfed infant because they can enter the breast milk. Summer tends to be a time when more of these products are used on the skin because of exposure to insects and sun. The e[...]Article : texte imprimé
Pregnancy and breastfeeding are two different things. Not only is teratogenicity not an issue postpartum but also infant exposure to drugs in breast milk is usually much less than the exposure during pregnancy. Nevertheless, sometimes authors do[...]Article : texte imprimé
Most concern focuses on the toxicity of drugs after the oral ingestion of drugs by nursing mothers. But, application of drugs to the skin of the mother raises additional issues. Is the dosage form important? Which drugs are absorbed sufficiently[...]