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Academy of Breastfeeding Medicine, Auteur ; Margaret M. Fleming, Auteur ; Katrina B. Mitchell, Auteur ; Philip O. Anderson, Auteur |Breastfeeding women may be required to undergo diagnostic imaging and/or nuclear medicine procedures at any point during lactation. Many women report being incorrectly instructed to discard (“pump and dump”) their breast milk or stop breastfeedi[...]Article : texte imprimé
Few comprehensive studies have been published on adverse drug reactions (ADRs) in breastfed infants from maternal medications. This column reviews the findings of two articles,1,2 plus seven additional articles published since the most recent ar[...]Article : texte imprimé
Use of alcohol in moderate amounts, for example, one drink with a meal, is unlikely to harm a breastfed infant as long as breastfeeding or pumping does not take place too soon after alcohol intake. Waiting 2–2.5 hours per drink will minimize inf[...]Article : texte imprimé
Occasionally an adverse drug reaction in a nursing infant is reported and becomes an “urban legend” that expands beyond reasonable limits. Such was the case of severe postoperative bleeding in a 4-week-old infant whose mother was taking the oral[...]Article : texte imprimé
Although many classes of drugs have been used for nausea and vomiting, few of the individual drugs have been studied well. Most of these drugs are used only for short periods of time, limiting risk to the breastfed infant. However, some commonly[...]Article : texte imprimé
Most antiepileptic drugs that have breastfeeding information reported appear to be acceptable to use during breastfeeding as single agents. Long-term follow-up data indicate that maternal carbamazepine, lamotrigine, phenytoin, and valproate caus[...]Article : texte imprimé
Many drugs are being investigated for treatment of COVID-19. The Medical Letter on Drugs and Therapeutics maintains an excellent, periodically updated and well-referenced table of anti-COVID-19 drugs that is free to download.1 Additional informa[...]Article : texte imprimé
The most commonly used antirejection drugs used after organ transplantation, cyclosporine, tacrolimus, corticosteroids, azathioprine and probably rituximab, are acceptable during breastfeeding. However, they should be used with caution while nur[...]Article : texte imprimé
Perhaps of greater immediate concern in the United States is the treatment of season influenza. As of February 21, 2020, 342 women of childbearing age (15–44 years) had been hospitalized in the United States with influenza during the current flu[...]Article : texte imprimé
Breastfeeding is discouraged in women with HIV in high-income countries, but this guidance is beginning to be questioned by some. Although transmission of HIV infection to infants is low with appropriate therapy, it is not zero. U.S. guidelines [...]Article : texte imprimé
Older drugs for MS, such as glatiramer, interferon beta, IVIG and methylprednisolone, appear to be acceptable to use during breastfeeding. The newer monoclonal antibodies, natalizumab and rituximab appear promising in breastfeeding, but safety i[...]Article : texte imprimé
Most drugs used in the treatment of inflammatory bowel disease are compatible with breastfeeding. One exception is tofacitinib that requires cessation of breastfeeding if it is used. The use of weekly methotrexate is controversial. Although no a[...]Article : texte imprimé
The complex issues surrounding cannabis* use during breastfeeding have been well detailed by Mourh and Rowe in this issue of Breastfeeding Medicine.1 One topic that requires some amplification is that of assay methodology. The high fat solubilit[...]Article : texte imprimé
Choosing Medication Alternatives During Breastfeeding, Avoiding Alternative Facts : LactMed ® Update
Most drugs studied in nursing mothers present a low risk for the breastfed infant. But some drugs have more suitable alternatives available, often because of more extensive published safety data. In these cases, similar medications are listed in[...]Article : texte imprimé
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Philip O. Anderson, Auteur ; La Leche League France, Traducteur |Article : texte imprimé
Philip O. Anderson, Auteur ; Palika Datta, Auteur ; Peter Gerrit Johannes ter Horst, Auteur |Article : texte imprimé
Philip O. Anderson, Auteur ; Catherine Leggett, Auteur ; La Leche league France, Traducteur |Article : texte imprimé
Philip O. Anderson, Auteur ; Elizabeth V. Asztalos, Auteur ; La Leche League France, Auteur |Article : texte imprimé
Philip O. Anderson, Auteur ; F. Rohr, Auteur ; EF. Nash, Auteur |Article : texte imprimé
Philip O. Anderson, Auteur ; La Leche League France, Traducteur |"La maladie de Raynaud touche 3-5 % de la population, sa prévalence étant environ 4 fois plus élevée chez les femmes que chez les hommes. Elle se caractérise par un vasospasme des vaisseaux sanguins au niveau des extrémités, et ce vasospasme peu[...]Article : texte imprimé
Philip O. Anderson, Auteur ; Jason B. Sauberan, Auteur |Article : texte imprimé
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Domperidone is a drug that seems to evoke reactions from lactation professionals ranging from consternation to anger, and in the extreme, to conspiracy theories about backroom deals between regulators and infant formula companies. Although compl[...]Article : texte imprimé
Drugs are not the preferred method of weight loss, and information on them during breastfeeding is almost nonexistent. Several of them might cause adverse effects on the infant or on lactation itself. Nonabsorbable products such as orlistat and [...]Article : texte imprimé
Several genetic diseases have had advances in treatment, including some new drugs. This column will focus on a few of these drug therapies and their implications for breastfeeding. More detailed information and references on specific drugs can b[...]Article : texte imprimé
Raynaud's phenomenon (RP) occurs in 3–5% of the population, with the rate of occurrence in women about four times that in men. It is caused by vasospasm of the blood vessels in the extremities, including the nipple. RP of the nipple can be extre[...]Article : texte imprimé
Drug treatment of RA need not be a barrier to breastfeeding; however, careful drug selection is important. Low-dose methotrexate is a mainstay of therapy, and limited data have found no indication of toxicity in breastfed infants, but more data [...]Article : texte imprimé
The plethora of new drugs to treat hepatitis presents a confusing array of options to treat the nursing mother. LactMed has recently undertaken an extensive review of these drugs to put them into a consistent context. [extrait de l'article]Article : texte imprimé
Discussion of medication use during breastfeeding usually centers around potential harm to the nursing infant. However, another important consideration is that of drugs that interfere with lactation. These can be divided into two subcategories: [...]Article : texte imprimé
This column discusses medications that affect lactation when given postpartum. The previous column discussed medications that affect the establishment of lactation when given before or during delivery. Additional details and literature reference[...]Article : texte imprimé
Information on general anesthesia and breastfeeding is incomplete, and often of poor quality, but some generalizations can be made. General anesthesia might delay lactation postoperatively somewhat, but nursing right before anesthesia might redu[...]Article : texte imprimé
Most drugs used to treat IBS are acceptable to use during breastfeeding. Although several medications used in IBS have no information on use in nursing mothers, they appear to pose low risk to the breastfed infant. Dicyclomine and eluxadoline sh[...]Article : texte imprimé
Herbal medication use during breastfeeding has not been well studied, but a few cases of adverse reactions in breastfed infants have been reported. Herbals can adversely affect the nursing mother in several ways, including direct adverse effects[...]Article : texte imprimé
Philip O. Anderson, Auteur ; Veronica Valdés, Auteur |Article : texte imprimé
The LactMed database contains information on drugs to which breastfeeding mothers may be exposed, and the possible adverse effects of those medications in the nursing infant. LactMed is written under contract with the Specialized Information Ser[...]Article : document cartographique imprimé
Clinicians involved with breastfeeding have probably heard the generalization that most drugs are compatible with breastfeeding except for cancer chemotherapy and radioactive agents. In fact, as with most broad generalizations, this statement is[...]Article : texte imprimé
Constipation is not uncommon in nursing mothers, especially in the immediate postpartum period wherein some constipation is the result of prescribed opioids. A wide variety of products are available to prevent and treat constipation, ranging fro[...]Nouveauté
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Lidocaine and bupivacaine have extensive documented use in nursing mothers and are the preferred injectable local anesthetics during breastfeeding. Topical anesthetics known to cause systemic toxicity after oral ingestion, such as benzocaine, co[...]Article : texte imprimé
No routine vaccines are contraindicated in nursing mothers. Yellow fever vaccine should not be given to mothers who are breastfeeding an infantArticle : texte imprimé
For information on the use and safety of drugs in nursing mothers, the answers you get also depend on where you look for the answers. Several studies have compared the information provided in different sources. A 2007 article found wide variatio[...]Article : texte imprimé
It is feasible for migraineurs to breastfeed. If nondrug alternatives are ineffective, several prophylactic drugs such as certain anticonvulsants, beta-blockers, and onabotulinumtoxinA are safe for the breastfed infant. Although the new injectab[...]Article : texte imprimé
The conventional model of drug passage into breastmilk states that large molecules such as maternal immunoglobulins can pass into colostrum because spaces between mammary epithelial cells are open. Then, these pores begin to close at the onset o[...]Article : texte imprimé
Overall, several generalizations can be made: (1) most mothers receiving mAbs have unmeasurable or extremely low levels of the mAb in their breast milk; (2) about half of the mAb will be digested in the infant's tract; (3) negligible amounts of [...]Article : texte imprimé
The passage of food-borne toxins into breast milk is poorly documented, but appears to be possible and quite dangerous with some maternal poisonings. It is safest to assume that all of the most deadly toxins can potentially be transmitted to the[...]Article : document cartographique imprimé
Most radiopharmaceuticals consist of two parts: the radioactive isotope and a pharmacologically inert carrier molecule to which it is attached. The carrier molecule is designed to take the radiopharmaceutical to its intended target in the body b[...]Article : texte imprimé
Of the wide range of drugs used to treat respiratory conditions, few have any serious concerns for use in nursing mothers. Inhaled drugs used for respiratory conditions, including nasal sprays, pose little or no risk to the breastfed infant. Ora[...]Article : texte imprimé
The use of personal care products poses some potential risks to the breastfed infant because they can enter the breast milk. Summer tends to be a time when more of these products are used on the skin because of exposure to insects and sun. The e[...]Article : texte imprimé
Pregnancy and breastfeeding are two different things. Not only is teratogenicity not an issue postpartum but also infant exposure to drugs in breast milk is usually much less than the exposure during pregnancy. Nevertheless, sometimes authors do[...]Article : texte imprimé
Most concern focuses on the toxicity of drugs after the oral ingestion of drugs by nursing mothers. But, application of drugs to the skin of the mother raises additional issues. Is the dosage form important? Which drugs are absorbed sufficiently[...]
